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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: TRIM37 All Species: 24.85
Human Site: S595 Identified Species: 54.67
UniProt: O94972 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O94972 NP_001005207.1 964 107906 S595 H G Y V G S S S R I S R R T H
Chimpanzee Pan troglodytes XP_511914 1136 126597 S767 H G Y V G S S S R I S R R T H
Rhesus Macaque Macaca mulatta XP_001107200 963 107823 S594 H G Y V G S S S R I S R R T H
Dog Lupus familis XP_853278 962 107845 S596 H G Y V G A S S R M S R R A H
Cat Felis silvestris
Mouse Mus musculus Q6PCX9 961 107641 S596 H S Y V G A S S R M S R R T H
Rat Rattus norvegicus NP_001101758 1008 112512 S596 H S Y V G A S S R M S R R A H
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509422 1125 125171 S622 H G Y A N A S S R P S R R T G
Chicken Gallus gallus NP_001006224 983 108754 G598 H G Y T S A S G R P S R R G G
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_695826 957 105706 V584 A G G S G A G V R G S R R G A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_396821 1007 112716 Q616 S S P T V N Q Q Q L N L L S S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_791708 455 52591 E94 D K C E L H N E K L S V Y C W
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 84.5 98.8 94.8 N.A. 92.5 88.3 N.A. 71.7 79.7 N.A. 65.4 N.A. N.A. 40.1 N.A. 36.9
Protein Similarity: 100 84.5 99.3 96.7 N.A. 95.1 91.1 N.A. 77 85.8 N.A. 74.4 N.A. N.A. 56.4 N.A. 42.2
P-Site Identity: 100 100 100 80 N.A. 80 73.3 N.A. 66.6 53.3 N.A. 40 N.A. N.A. 0 N.A. 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 93.3 86.6 N.A. 73.3 60 N.A. 46.6 N.A. N.A. 33.3 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 55 0 0 0 0 0 0 0 19 10 % A
% Cys: 0 0 10 0 0 0 0 0 0 0 0 0 0 10 0 % C
% Asp: 10 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 0 0 10 0 0 0 10 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 64 10 0 64 0 10 10 0 10 0 0 0 19 19 % G
% His: 73 0 0 0 0 10 0 0 0 0 0 0 0 0 55 % H
% Ile: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 10 0 0 0 0 19 0 10 10 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 28 0 0 0 0 0 % M
% Asn: 0 0 0 0 10 10 10 0 0 0 10 0 0 0 0 % N
% Pro: 0 0 10 0 0 0 0 0 0 19 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 10 10 10 0 0 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 82 0 0 82 82 0 0 % R
% Ser: 10 28 0 10 10 28 73 64 0 0 91 0 0 10 10 % S
% Thr: 0 0 0 19 0 0 0 0 0 0 0 0 0 46 0 % T
% Val: 0 0 0 55 10 0 0 10 0 0 0 10 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % W
% Tyr: 0 0 73 0 0 0 0 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _